The ecf contains extracellular matrices ecms that act as fluids of suspension for cells and molecules inside the ecf. In addition to the balance of water and electrolytes acid base balance is important for the normal functioning of body cells and is also highly regulated. The volume of ecf is typically 15l of which 12l is interstitial fluid and 3l is plasma. Fluids in the human body function to provide digestion lubrication nutrient and oxygen transportation and protection. Although the ph of blood ranges from 735 745 the ph of other body fluids is different. At room temperature a ph measurement of 7 is neutral meaning that there is an equal concentration of hydrogen and hydroxide oh ions.
A 14 means there is a very low concentration of hydrogen ions while 1 means there is a very high concentration of hydrogen ions. The ph of extracellular fluid is tightly regulated by buffers and maintained around 74. Ph measurement hco 3 a pco2 protein buffers. While the ph of different body fluids varies blood ph is restricted to between 735 745ph but as the main transporter of substances is highly susceptible to changes in ph. Overall levels of acidity or alkalinity are measured on a ph scale and must be carefully controlled in each body fluid. A change in the ratio influences the performance of the electrode.
Ph indicates the level of h ions where low ph indicates too many h ions. A measuring system for ph measurement in bodily fluids consisting of sensing electrodes according to claim 1 placed above each other. Some amino acids have acid or basic side chains his lys arg glu asp. To perform these functions the acid levels must be varied to match the bodily function. A low pleural fluid ph implies a high metabolic activity in the pleural space. Your blood has a normal ph range of 735 to 745this means that blood is naturally slightly alkaline or basic.
We use status of bicarbonate buffer for clinical evaluation of patients acid base balance. A reduced ph typically 720 12 has been shown to be a robust marker for instituting intercostal tube drainage in patients with suspected pleural infection 13 14 and is used as an entry criterion for clinical studies of pleural infection 15 16in malignant pleural effusion low pleural fluid ph correlates. Ph of different body fluids. The ph scale goes from 0 highly acidic to 14 highly basic. In comparison your stomach acid has a ph of around 15 to 35this makes it acidic. The pleural fluid ph was determined within 20 min after being collected anaerobically by a blood gas machine ciba corning model 288 ph meter corning ph meter 610a and ph indicator strip.
Body proteins plasma proteins and intracellular are the most abundant and the most powerful buffer system in whole organism. The antimony layer 2 on the thicker part of the body 1 has a ring shape and it is in contact with the measured solution.